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JAEA Reports

Development of fundamental technologies for domestic production of medical radioisotope (technetium-99m); The First and second phase report (FY2014-2020)

Project 6 Meeting Members for Tsukuba International Strategic Zone

JAEA-Review 2021-016, 102 Pages, 2021/11

JAEA-Review-2021-016.pdf:12.76MB

In December 2011, the Prime Minister designated Tsukuba and some areas in Ibaraki Prefecture as "Comprehensive Special Zones". In the Tsukuba International Strategic Zone, nine advanced research and development (R&D) projects are underway with the goal of promoting industrialization of life innovation and green innovation utilizing the science and technology in Tsukuba. In these projects, the domestic production of medical radioisotope (Technetium-99m, $^{rm 99m}$ Tc) was certified as a new project in October 2013, and R&D have been performed in collaboration with related organizations with Japan Atomic Energy Agency (JAEA) as the project leader. Japan is the third largest consumer of molybdenum-99 ( $^{99}$ Mo) after the United States and Europe, and all $^{99}$ Mo are imported. Supply will be insufficient if overseas reactors are shut down due to trouble or if transportation (air and land transportations) is stopped due to volcanic eruptions and some accidents. Thus, early domestic production of $^{99}$ Mo is strongly required. This project is a technology development aimed at domestic production of $^{99}$ Mo, which is a raw material of $^{rm 99m}$ Tc used as a diagnostic agent. This report summarizes the activities carried out in the first and second phase of the domestic production of medical radioisotope ( $^{rm 99m}$ Tc) (here referred to as the "Project 6") in Tsukuba International Strategic Zone (FY2014-2020).

Journal Articles

Mesoporous alumina-titania composites with enhanced molybdenum adsorption towards medical radioisotope production

Benu, D. P.*; Earnshaw, J.*; Ashok, A.*; Tsuchiya, Kunihiko; Saptiama, I.*; Yuliarto, B.*; Suendo, V.*; Mukti, R. R.*; Fukumitsu, Nobuyoshi*; Ariga, Katsuhiko*; et al.

Bulletin of the Chemical Society of Japan, 94(2), p.502 - 507, 2021/02

https://doi.org/10.1246/bcsj.20200282

Times Cited Count：11 Percentile：65.6(Chemistry, Multidisciplinary)

no abstracts in English

Journal Articles

Radiochemical research for the advancement of $^{99}$ Mo/ $^{rm 99m}$ Tc generator by (n,) method, 2

Fujita, Yoshitaka; Seki, Misaki; Namekawa, Yoji*; Nishikata, Kaori; Kato, Yoshiaki; Sayato, Natsuki; Tsuchiya, Kunihiko; Sano, Tadafumi*; Fujihara, Yasuyuki*; Hori, Junichi*; et al.

KURNS Progress Report 2019, P. 157, 2020/08

https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2019/ProgressReport2019_online.pdf#page=173

no abstracts in English

Journal Articles

Radiochemical research for the advancement of $^{99}$ Mo/ $^{rm 99m}$ Tc generator by (n,) method

Fujita, Yoshitaka; Seki, Misaki; Namekawa, Yoji*; Nishikata, Kaori; Kimura, Akihiro; Shibata, Akira; Sayato, Natsuki; Tsuchiya, Kunihiko; Sano, Tadafumi*; Fujihara, Yasuyuki*; et al.

KURNS Progress Report 2018, P. 155, 2019/08

https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2018/KURNS_Progress_Report2018_web.pdf

no abstracts in English

Journal Articles

Development of $^{99}$ Mo/ $^{99m}$ Tc generator for the $^{99}$ Mo/ $^{99m}$ Tc domestic production

Fukumitsu, Nobuyoshi*; Tsuchiya, Kunihiko; Ariga, Katsuhiko*; Yamauchi, Yusuke*

Isotope News, (742), p.20 - 24, 2016/02

http://www.jrias.or.jp/books/pdf/201602_TRACER_FUKUMITSU_HOKA.pdf

no abstracts in English

Journal Articles

Synthesis of new adsorbents for Mo as an RI generator

*; *; *; *; *; Tanase, Masakazu; Kurosawa, Kiyoyuki

Nihon Kagakkai-Shi, 0(10), p.888 - 894, 1996/00

no abstracts in English

Oral presentation

Development of high performance Mo adsorbents

Fukumitsu, Nobuyoshi*; Yamauchi, Yusuke*; Saptiama, I.*; Ariga, Katsuhiko*; Hatano, Kentaro*; Kumada, Hiroaki*; Fujita, Yoshitaka; Tsuchiya, Kunihiko

no journal, ,

no abstracts in English

Oral presentation

Development of effective adsorbent for Molybdenum

Fukumitsu, Nobuyoshi*; Yamauchi, Yusuke*; Saptiama, I.*; Ariga, Katsuhiko*; Hatano, Kentaro*; Kumada, Hiroaki*; Fujita, Yoshitaka; Tsuchiya, Kunihiko

no journal, ,

no abstracts in English

Oral presentation

Mo adsorption and $^{99m}$ Tc elution properties of alumina using (n, ) $^{99}$ Mo

Fujita, Yoshitaka; Seki, Misaki; Sano, Tadafumi*; Suzuki, Tatsuya*; Kitagawa, Tomoya*; Nishikata, Kaori; Matsukura, Minoru*; Tsuchiya, Kunihiko

no journal, ,

no abstracts in English

Oral presentation

Development of mesoporous alumina-titanium complex aiming at domestic production of $^{99}$ Mo/ $^{99m}$ Tc

Fukumitsu, Nobuyoshi*; Yamauchi, Yusuke*; Kaneti, Y. V.*; Benu, D. P.*; Saptiama, I.*; Ariga, Katsuhiko*; Hatano, Kentaro*; Kumada, Hiroaki*; Fujita, Yoshitaka; Tsuchiya, Kunihiko

no journal, ,

no abstracts in English

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Development of fundamental technologies for domestic production of medical radioisotope (technetium-99m); The First and second phase report (FY2014-2020)

Mesoporous alumina-titania composites with enhanced molybdenum adsorption towards medical radioisotope production

Radiochemical research for the advancement of $^{99}$ Mo/ $^{rm 99m}$ Tc generator by (n,) method, 2

Radiochemical research for the advancement of $^{99}$ Mo/ $^{rm 99m}$ Tc generator by (n,) method

Development of $^{99}$ Mo/ $^{99m}$ Tc generator for the $^{99}$ Mo/ $^{99m}$ Tc domestic production

Synthesis of new adsorbents for Mo as an RI generator

Development of high performance Mo adsorbents

Development of effective adsorbent for Molybdenum

Mo adsorption and $^{99m}$ Tc elution properties of alumina using (n, ) $^{99}$ Mo

Development of mesoporous alumina-titanium complex aiming at domestic production of $^{99}$ Mo/ $^{99m}$ Tc